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Peptide comparisons

Compare peptides by human evidence, FDA or compounding status, product-quality risk, and the claims people usually group together.

Interactive tool

Stack evidence checker

Select two to four compounds to see evidence grades, public verdicts, regulatory status, and any blend record that matches the combination.

BPC-157 / TB-500

BPC-157 vs TB-500

BPC-157 has more public confusion; TB-500 claims often mix up product identity, fragments, and related molecules, so the exact substance matters.

KPV / BPC-157

KPV vs BPC-157

KPV is more mechanism-heavy; BPC-157 carries stronger regulatory and product-quality warnings. The useful comparison is what each claim actually rests on.

Semaglutide / Tirzepatide

Semaglutide vs Tirzepatide

Both have approved products; the useful comparison is efficacy, tolerability, approved labeling, and where compounded or off-label marketing changes the conversation.

Retatrutide / Tirzepatide

Retatrutide vs Tirzepatide

Tirzepatide is the established, regulator-reviewed option; retatrutide has striking phase 2 weight-loss numbers but no approved product and an active gray market.

CJC-1295 DAC / CJC-1295 no DAC

CJC-1295 DAC vs CJC-1295 no DAC

The DAC version trades physiologic GH pulses for convenience; the no-DAC form (Mod GRF 1-29) is the short-acting backbone used in the classic human pharmacology work and in most community stacks.

Ipamorelin / GHRP-2

Ipamorelin vs GHRP-2

Both raise growth hormone in human challenge studies; ipamorelin is preferred in clinic and community discussion because comparative work found it did not raise ACTH or cortisol where GHRP-2 did.

Semax / Selank

Semax vs Selank

Semax is positioned for cognition and focus, selank for anxiety; both rest mainly on Russian domestic literature, with semax having the deeper research history.

Melanotan-1 / Melanotan-2

Melanotan-1 vs Melanotan-2

Melanotan-1 (the afamelanotide lineage) reached an approved implant for a rare photosensitivity disease; melanotan-2 is the unapproved community staple with broader effects and more side effects.

Tesamorelin / Sermorelin

Tesamorelin vs Sermorelin

Tesamorelin is FDA-approved for HIV-associated lipodystrophy with randomized visceral-fat trials behind it; sermorelin survived as a clinic product whose adult anti-aging claims were never established in trials.

IGF-1 LR3 / IGF-1 DES

IGF-1 LR3 vs IGF-1 DES

LR3 is the long-acting version used daily; DES is the shorter, more potent version used around workouts. Neither has human trials, and both carry real hypoglycemia risk by mechanism.

MOTS-c / SS-31 / Elamipretide

MOTS-c vs SS-31

MOTS-c is a mitochondrial-derived peptide with strong animal metabolic data and early human trials; SS-31 (elamipretide) spent years in clinical development and won a narrow FDA approval in 2025 for Barth syndrome.

GHRP-2 / GHRP-6

GHRP-2 vs GHRP-6

Both raise growth hormone in human challenge studies and both raise ACTH and cortisol alongside it. The practical differences are potency per microgram, hunger stimulation, and GHRP-2's Japanese diagnostic approval as pralmorelin.

Sermorelin / Ipamorelin

Sermorelin vs Ipamorelin

Sermorelin works the GHRH receptor side and ipamorelin the ghrelin-receptor side; clinics pair them because the two pathways amplify each other. Individually, both have thin adult outcome evidence.

Thymosin alpha-1 / Thymosin beta-4

Thymosin Alpha-1 vs Thymosin Beta-4

Thymosin alpha-1 is a 28-amino-acid immune peptide approved in dozens of countries with a defined schedule; thymosin beta-4 is a 43-amino-acid repair-associated protein whose market fragments (TB-500) are prohibited in sport.

Epitalon / DSIP

Epitalon vs DSIP

Epitalon is the longevity-framed tetrapeptide built on telomerase and melatonin-rhythm claims; DSIP is the older sleep-framed nonapeptide whose human literature is small, old, and inconsistent.

Melanotan-2 / PT-141

Melanotan-2 vs PT-141

PT-141 is bremelanotide, the refined MC4R-selective descendant that became an approved drug for hypoactive sexual desire; melanotan-2 is the unapproved parent peptide whose side effects revealed that pathway in the first place.

TB-500 / Thymosin beta-4

TB-500 vs Thymosin Beta-4

Thymosin beta-4 is a full-length 43-amino-acid protein with a real research literature; TB-500 is a market name usually attached to fragments of it. Evidence from one does not automatically transfer to the other.

Tesamorelin / CJC-1295 DAC

Tesamorelin vs CJC-1295 DAC

Tesamorelin is FDA-approved with randomized visceral-fat trials behind a defined daily schedule; CJC-1295 DAC offers weekly convenience through albumin binding but has no outcome trials and a non-physiologic elevation pattern.

BPC-157 / GHK-Cu

BPC-157 vs GHK-Cu

BPC-157 has strong rodent repair data and thin human data; GHK-Cu has a modest human cosmetic literature for topical use and little behind injectable systemic claims. The right comparison is route-by-route.

Epitalon / Pinealon

Epitalon vs Pinealon

Epitalon is the longevity-framed tetrapeptide built on telomerase and melatonin claims; pinealon is the cognition-framed tripeptide with an older CNS report behind it. Both rest almost entirely on the same research lineage.

Semaglutide / Cagrilintide

Semaglutide vs Cagrilintide

Semaglutide is the approved reference with years of label data; cagrilintide is a complementary satiety-pathway candidate whose real story is the CagriSema combination.

GHRP-2 / Hexarelin

GHRP-2 vs Hexarelin

Both are potent ghrelin-receptor agonists with cortisol and prolactin spillover. The practical differences are GHRP-2's Japanese diagnostic approval and hexarelin's faster desensitization.

MOTS-c / NAD+

MOTS-c vs NAD+

MOTS-c has compelling rodent metabolic data and almost no human administration data; NAD+ has real human IV studies that measured metabolites and tolerability, not benefits.

Thymalin / Thymosin alpha-1

Thymalin vs Thymosin Alpha-1

Thymosin alpha-1 is a single defined molecule with international approvals and a label schedule; thymalin is a thymus-extract mixture whose evidence is old, regional, and low-certainty.

Semax / Adamax

Semax vs Adamax

Semax has a real (if narrow and Russian) research history and drug registration; Adamax is a vendor-invented modification with no published literature of any kind, borrowing all of its parent's credibility.