Peptide profiles

Each page shows what human evidence exists, what regulators have said, which sources are cited, and where route, dose, or product-quality claims need caution.

Agrade

Semaglutide

The active ingredient behind Ozempic, Wegovy, and Rybelsus, useful for separating product-specific label evidence from compounded or research-use claims.

Full profile1 evidence area9 cited references1 use cases
Strong human evidenceApproved for specific use
Agrade

Tirzepatide

The active ingredient in Mounjaro and Zepbound, with strong product-specific evidence for type 2 diabetes, chronic weight management, and OSA in adults with obesity.

Full profile1 evidence area14 cited references1 use cases
Strong human evidenceApproved for specific use
Bgrade

Retatrutide

An investigational once-weekly triple agonist peptide with strong human weight-loss and glycemic-control signals, unresolved approval status, and high gray-market product-quality risk.

Full profile5 evidence areas14 cited references0 use cases
Moderate human evidenceInvestigational / not approved
Bgrade

Cagrilintide

An investigational long-acting amylin analogue with controlled human weight-management evidence and clear FDA limits around compounding and online product claims.

Full profile5 evidence areas7 cited references0 use cases
Moderate human evidenceInvestigational / not approved
Bgrade

CagriSema

Novo Nordisk's investigational cagrilintide-plus-semaglutide program, with phase 3 human weight-management evidence and separate risks for compounded or online combinations.

Full profile5 evidence areas12 cited references0 use cases
Strong human evidenceInvestigational / not approved
Dgrade

Cartalax

A cartilage-oriented tripeptide where preclinical chondrocyte support, weak legacy symptom reports, and product-identity drift need to be kept separate.

Full profile2 evidence areas15 cited references0 use cases
Limited human evidenceVaries by product and jurisdiction
Dgrade

BPC-157

A heavily promoted repair and gut peptide where human evidence is still limited to a few narrow sources and FDA-flagged compounding concerns.

Full profile2 evidence areas7 cited references2 use cases
Limited human evidenceNot FDA-approved for listed uses
Dgrade

KPV

A short alpha-MSH-derived peptide motif with preclinical gut-inflammation, delivery, and antimicrobial literature, but no direct human KPV efficacy evidence found.

Full profile2 evidence areas8 cited references2 use cases
Mostly preclinicalInvestigational / not approved
Cgrade

GHK-Cu

A copper-binding tripeptide with route-specific topical skin and wound evidence, plus much weaker systemic, hair, blend, and injectable claim areas.

Full profile2 evidence areas7 cited references2 use cases
Moderate human evidenceVaries by product and jurisdiction
Egrade

TB-500

A recovery-focused peptide name where the first question is whether the source means the TB-500 fragment, full-length thymosin beta-4, or a market vial.

Full profile2 evidence areas4 cited references1 use cases
Evidence unclearInvestigational / not approved
Dgrade

Thymosin beta-4

A full-length thymosin beta-4 topic with human ophthalmic, wound, and registry context that must stay separate from TB-500 fragment claims.

Full profile4 evidence areas27 cited references0 use cases
Limited human evidenceInvestigational / not approved
Dgrade

LL-37

LL-37 has host-defense biology, narrow human chronic-wound evidence, and prominent FDA compounding-risk concerns.

Full profile4 evidence areas4 cited references1 use cases
Limited human evidenceInvestigational / not approved
Dgrade

MOTS-c

A mitochondrial-derived peptide with human biomarker and association data, preclinical metabolic mechanism work, and no posted intervention results yet.

Full profile2 evidence areas8 cited references1 use cases
Limited human evidenceInvestigational / not approved
Dgrade

Semax

A neuropeptide analog discussed for stroke, optic nerve disease, focus, mood, stress, and route choice, with mostly intranasal CNS-oriented published evidence and a weaker subcutaneous route narrative from clinic and anecdotal contexts.

Full profile4 evidence areas11 cited references1 use cases
Limited human evidenceVaries by product and jurisdiction
Egrade

Adamax

A Semax-family designer peptide marketed as the longer-Semax option, with far less direct evidence than the online nootropic pitch suggests.

Full profile3 evidence areas11 cited references0 use cases
Evidence unclearVaries by product and jurisdiction
Dgrade

Pinealon

A short EDR tripeptide discussed for neuroprotection, cognition, and sleep-adjacent claims, with support still concentrated in reviews, preclinical work, and unresolved source questions.

Full profile2 evidence areas6 cited references2 use cases
Mostly preclinicalInvestigational / not approved
Dgrade

Epitalon

A short AEDG tetrapeptide discussed in circadian, melatonin, telomere, retina, and longevity contexts, where public claims often exceed direct clinical evidence.

Full profile2 evidence areas11 cited references3 use cases
Mostly preclinicalInvestigational / not approved
Dgrade

DSIP

A sleep-associated nonapeptide with older human insomnia studies, unresolved biology, and modern emideltide/DSIP claims that need careful source-by-source reading.

Full profile2 evidence areas7 cited references2 use cases
Limited human evidenceInvestigational / not approved
Cgrade

Thymosin alpha-1

An immunomodulatory thymalfasin peptide with older chronic-hepatitis-B evidence, non-U.S. Zadaxin labeling, mixed sepsis and COVID literature, and broad clinic or gray-market immune-support marketing.

Full profile4 evidence areas22 cited references1 use cases
Limited human evidenceVaries by product and jurisdiction
Bgrade

SS-31 / Elamipretide

A cardiolipin-targeting tetrapeptide with FDA accelerated approval under the Forzinity brand for a narrow Barth syndrome indication, plus mixed or negative non-Barth development areas.

Full profile5 evidence areas54 cited references1 use cases
Moderate human evidenceApproved for specific use
Cgrade

ARA-290

An investigational erythropoietin-derived peptide studied mainly in sarcoidosis-associated small-fiber neuropathy and in an early type 2 diabetes neuropathy setting.

Full profile3 evidence areas12 cited references0 use cases
Limited human evidenceInvestigational / not approved
Dgrade

GHK-Cu + KPV Blend

A marketed skin and inflammation blend built from two different source areas: topical GHK-Cu skin data and preclinical KPV barrier biology.

Full profile4 evidence areas17 cited references0 use cases
Mostly preclinicalInvestigational / not approved
Egrade

Wolverine Blend

A BPC-157 plus TB-500 blend marketed for repair and recovery, with evidence drawn from component and market sources rather than a fixed commercial blend trial.

Full profile4 evidence areas13 cited references0 use cases
Limited human evidenceInvestigational / not approved
Dgrade

Glutathione

An endogenous tripeptide explainer that separates glutathione biology from supplement, cosmetic, oncology-adjunct, clinic IV, and sterile-product claims.

Full profile5 evidence areas16 cited references0 use cases
Limited human evidenceNot FDA-approved for listed uses
Agrade

Tesamorelin

An FDA-approved growth hormone-releasing factor analog with narrow human evidence for reducing excess abdominal fat in adults with HIV-associated lipodystrophy.

Full profile4 evidence areas5 cited references0 use cases
Strong human evidenceApproved for specific use
Bgrade

Sermorelin

A 29-amino-acid GHRH fragment with historical Geref product context in pediatric growth-hormone deficiency and pituitary growth-hormone reserve evaluation.

Full profile5 evidence areas6 cited references0 use cases
Moderate human evidenceVaries by product and jurisdiction
Cgrade

CJC-1295 DAC

A DAC-linked GHRH analog with healthy-adult GH and IGF-1 pharmacology studies, a terminated HIV visceral-obesity registry context, and no FDA-approved drug product.

Full profile5 evidence areas4 cited references0 use cases
Limited human evidenceInvestigational / not approved
Egrade

CJC-1295 no DAC

A non-DAC CJC-1295 / Modified GRF identity summary, kept separate from DAC-specific CJC-1295 evidence.

Full profile3 evidence areas7 cited references0 use cases
Evidence unclearInvestigational / not approved
Dgrade

Ipamorelin

An investigational growth hormone secretagogue with narrow human pharmacology evidence, postoperative-ileus registry context, and direct FDA compounding-policy caution.

Full profile4 evidence areas4 cited references0 use cases
Limited human evidenceInvestigational / not approved
Cgrade

Kisspeptin-10

A 10-amino-acid kisspeptin research peptide with small human reproductive-endocrinology physiology studies and completed ClinicalTrials.gov development records, but no approved routine-use labeling.

Full profile4 evidence areas10 cited references1 use cases
Limited human evidenceInvestigational / not approved
Cgrade

Gonadorelin

A synthetic GnRH decapeptide with historical Lutrepulse human approval and specialist endocrine research context, while current U.S. DailyMed label visibility is veterinary rather than routine human-use labeling.

Full profile4 evidence areas7 cited references0 use cases
Limited human evidenceVaries by product and jurisdiction
Agrade

Setmelanotide

An FDA-approved cyclic peptide MC4 receptor agonist for narrow rare-obesity contexts tied to acquired hypothalamic obesity, Bardet-Biedl syndrome, and POMC, PCSK1, or LEPR deficiency.

Full profile5 evidence areas6 cited references0 use cases
Strong human evidenceApproved for specific use
Agrade

Afamelanotide

An FDA-approved MC1 receptor agonist product for increasing pain-free light exposure in adults with erythropoietic protoporphyria and a history of phototoxic reactions.

Full profile5 evidence areas5 cited references0 use cases
Strong human evidenceApproved for specific use
Bgrade

Melanotan-1

A melanocortin alias term tied to regulated afamelanotide / Scenesse evidence, separate from tanning-peptide market claims.

Full profile5 evidence areas6 cited references0 use cases
Strong human evidenceVaries by product and jurisdiction
Dgrade

Melanotan-2

An unapproved synthetic cyclic alpha-MSH analog most often discussed around tanning, libido, appetite, and online peptide products, where the clearest evidence points to regulatory and product-quality risk rather than dependable benefit.

Full profile4 evidence areas8 cited references1 use cases
Limited human evidenceNot FDA-approved for listed uses
Agrade

PT-141

A cyclic melanocortin receptor agonist with an FDA-approved bremelanotide product context for acquired, generalized HSDD in premenopausal women.

Full profile5 evidence areas5 cited references1 use cases
Strong human evidenceApproved for specific use
Agrade

Desmopressin

A synthetic vasopressin analog with approved product contexts for antidiuretic replacement in central diabetes insipidus and product-specific nocturnal-polyuria treatment.

Full profile4 evidence areas4 cited references0 use cases
Strong human evidenceApproved for specific use
Agrade

Oxytocin

A synthetic nonapeptide with approved Pitocin obstetric-medicine labeling and different source support around intranasal neuro-social claims.

Full profile5 evidence areas4 cited references1 use cases
Strong human evidenceApproved for specific use
Agrade

Vasopressin

A synthetic arginine vasopressin product approved for inpatient pressor support in adults with vasodilatory shock who remain hypotensive despite fluids and catecholamines.

Full profile5 evidence areas5 cited references0 use cases
Strong human evidenceApproved for specific use
Egrade

Bacteriostatic water

A peptide-adjacent reference for BAC water: sterile preserved water that explains reconstitution volume, concentration math, and quality checks around lyophilized peptide vials.

Full profile1 evidence area1 cited references0 use cases
Evidence unclearApproved for specific use
Dgrade

L-Carnitine

Levocarnitine is a peptide-adjacent clinic-market term. Official medical labeling is a better anchor than performance or wellness protocols.

Full profile1 evidence area1 cited references0 use cases
Limited human evidenceApproved for specific use
Dgrade

Methylene Blue

Methylene blue is a redox-active drug that also appears in nootropic, mitochondrial, and longevity-market discussions. The official acquired-methemoglobinemia label is the clearest medical reference point.

Full profile1 evidence area1 cited references0 use cases
Limited human evidenceApproved for specific use
Dgrade

NAD+

A peptide-adjacent coenzyme reference that separates NAD+ cell biology from clinic, infusion, oral, nasal, and product-quality claims.

Full profile3 evidence areas8 cited references1 use cases
Limited human evidenceNot FDA-approved for listed uses
Dgrade

DMSO

A DMSO reference that separates the official RIMSO-50 bladder-irrigant label from broader peptide-adjacent solvent, carrier, topical, and clinic-market claims.

Full profile1 evidence area1 cited references0 use cases
Limited human evidenceApproved for specific use
Dgrade

AOD-9604

AOD-9604 is a modified growth-hormone fragment developed as an anti-obesity drug and abandoned after trials failed to show meaningful weight loss. It remains widely marketed for fat loss, where the evidence does not support the claims.

Full profileSingle peptideRepair and recovery
Mostly preclinicalNot FDA-approved for listed uses
Egrade

HGH Fragment 176-191

HGH Fragment 176-191 is the unmodified C-terminal fragment of growth hormone, discussed for fat loss. Unlike its derivative AOD-9604, it has no human clinical literature to speak of, and community use rests on animal and mechanistic reasoning.

Full profileAlternate nameRepair and recovery
Evidence unclearNot FDA-approved for listed uses
Egrade

CJC-1295 no DAC + Ipamorelin

CJC-1295 no DAC plus ipamorelin is the most common growth-hormone secretagogue stack, sold as a fixed blend. The component molecules have separate, limited human pharmacology; the combination itself has no controlled human evidence.

Full profileBlendGrowth hormone and secretagogues
Evidence unclearNot FDA-approved for listed uses
Egrade

Sermorelin + Ipamorelin

Sermorelin plus ipamorelin is a clinic-formulated growth-hormone combination used in anti-aging programs. The components are individually discussed elsewhere; the blend has no controlled human evidence of its own.

Full profileBlendGrowth hormone and secretagogues
Evidence unclearNot FDA-approved for listed uses
Cgrade

GHRP-2

GHRP-2 (pralmorelin) is a growth-hormone secretagogue with real human physiology literature and approval in Japan as a diagnostic agent. Broader muscle, recovery, and anti-aging claims are extrapolations from its hormone effect.

Full profileSingle peptideGrowth hormone and secretagogues
Limited human evidenceVaries by product and jurisdiction
Dgrade

GHRP-6

GHRP-6 is an older synthetic secretagogue that reliably raises growth hormone in human challenge studies. Outcome data for muscle, fat loss, recovery, or anti-aging do not exist, and it carries the class's cortisol and appetite spillover.

Full profileSingle peptideGrowth hormone and secretagogues
Limited human evidenceNot FDA-approved for listed uses
Dgrade

Hexarelin

Hexarelin is the most potent common GHRP-class secretagogue, with human endocrine challenge literature but no outcome trials. Community use is limited by desensitization concerns and the class's strongest cortisol and prolactin spillover.

Full profileSingle peptideGrowth hormone and secretagogues
Limited human evidenceNot FDA-approved for listed uses
Egrade

IGF-1 LR3

IGF-1 LR3 is a long-acting modified IGF-1 analog sold for muscle growth. The modification that makes it popular has no human clinical literature, and the pharmacology carries real hypoglycemia risk.

Full profileSingle peptideMuscle growth and performance
Evidence unclearNot FDA-approved for listed uses
Egrade

IGF-1 DES

IGF-1 DES is a shortened, more potent IGF-1 variant discussed for localized muscle growth. It shares the same absence of human evidence and the same hypoglycemia mechanism risk as IGF-1 LR3.

Full profileSingle peptideMuscle growth and performance
Evidence unclearNot FDA-approved for listed uses
Dgrade

Selank

Selank is a Russian-developed intranasal anxiolytic peptide with small domestic trials behind it. Outside that literature, controlled evidence is sparse and vendor-modified analogs muddy the category.

Full profileSingle peptideNeuro and cognition
Limited human evidenceNot FDA-approved for listed uses
Egrade

N-Acetyl Selank Amidate

N-Acetyl Selank Amidate is a vendor-modified selank analog marketed as longer-acting. It has no published human literature; everything claimed for it is extrapolated from plain selank.

Full profileSingle peptideNeuro and cognition
Evidence unclearNot FDA-approved for listed uses
Egrade

N-Acetyl Semax Amidate

N-Acetyl Semax Amidate is a vendor-modified semax analog marketed as longer-acting. Nothing published exists for the analog itself; every claim is borrowed from plain semax.

Full profileSingle peptideNeuro and cognition
Evidence unclearNot FDA-approved for listed uses
Cgrade

VIP

VIP (vasoactive intestinal peptide) is an endogenous peptide with human trial history as aviptadil in lung and inflammatory indications. Its clinic use in mold-illness (CIRS) protocols is a separate, unproven practice with real hypotension risk.

Full profileSingle peptideImmune and inflammation
Limited human evidenceNot FDA-approved for listed uses
Egrade

P21

P21 is a ciliary-neurotrophic-factor-derived peptide with animal cognition literature only. There is no meaningful human evidence and no consistent community protocol.

Full profileSingle peptideNeuro and cognition
Evidence unclearNot FDA-approved for listed uses
Egrade

KLOW Blend

KLOW is a vendor blend name, typically combining GHK-Cu and KPV with recovery peptides such as BPC-157. Composition varies by seller, and no component combination has controlled human evidence.

Full profileBlendSkin, hair, and cosmetic
Evidence unclearNot FDA-approved for listed uses
Dgrade

Thymalin

Thymalin is a thymus-extract peptide mixture with Soviet-era drug registration and gerontology literature behind it. Modern controlled evidence is lacking, and products outside that lineage are unverified.

Full profileSingle peptideImmune and inflammation
Limited human evidenceVaries by product and jurisdiction
Dgrade

Thymogen

Thymogen is a short thymic peptide registered as a nasal immune drug in Russia. Its evidence base is domestic and old; outside that context it is unstudied.

Full profileSingle peptideImmune and inflammation
Limited human evidenceVaries by product and jurisdiction
Dgrade

Livagen

Livagen is a Khavinson-lineage liver bioregulator peptide. The support is the lineage's own publications plus animal and cell work; nothing controlled in people.

Full profileSingle peptideMitochondrial and longevity
Mostly preclinicalNot FDA-approved for listed uses
Dgrade

Vesugen

Vesugen is a Khavinson-lineage vascular bioregulator peptide. Human material is two old, abstract-level Russian vascular reports; everything else is the lineage's cell and animal work.

Full profileSingle peptideMitochondrial and longevity
Mostly preclinicalNot FDA-approved for listed uses
Dgrade

Ovagen

Ovagen is a Khavinson-lineage bioregulator peptide marketed around liver and GI claims. The only human-adjacent material is a patent example; the rest is preclinical kidney work.

Full profileSingle peptideMitochondrial and longevity
Mostly preclinicalNot FDA-approved for listed uses
Dgrade

Chonluten

Chonluten is a Khavinson-lineage lung bioregulator peptide. Direct evidence is cell and animal work; the human respiratory claims come from secondary reviews and product pages.

Full profileSingle peptideMitochondrial and longevity
Mostly preclinicalNot FDA-approved for listed uses
Dgrade

Bronchogen

Bronchogen is a Khavinson-lineage respiratory bioregulator peptide. Support stops at preclinical lung biology and supplement-label material; no controlled human lung trial exists.

Full profileSingle peptideImmune and inflammation
Mostly preclinicalNot FDA-approved for listed uses
Dgrade

Pancragen

Pancragen is a Khavinson-lineage pancreatic bioregulator peptide. There is one early, unreplicated glucose signal in the lineage's reports and no modern controlled trial.

Full profileSingle peptideMetabolic and weight loss
Mostly preclinicalNot FDA-approved for listed uses
Dgrade

Follistatin-344

Follistatin-344 is a myostatin-binding protein isoform discussed for muscle growth. Animal myostatin-pathway data are real, but there are no human trials of injected follistatin for physique purposes.

Full profileSingle peptideMuscle growth and performance
Mostly preclinicalNot FDA-approved for listed uses
Dgrade

Follistatin-315

Follistatin-315 is the other commonly sold follistatin isoform, treated in community discussion as near-interchangeable with follistatin-344 despite the distinction. Human evidence is absent for both.

Full profileSingle peptideMuscle growth and performance
Mostly preclinicalNot FDA-approved for listed uses
Dgrade

ACE-031

ACE-031 is a soluble activin receptor that reached human trials for muscular dystrophy before development stopped after vascular adverse events. It remains a cautionary example of mechanism-first muscle claims.

Full profileSingle peptideMuscle growth and performance
Limited human evidenceInvestigational / not approved
Egrade

Myostatin propeptide

Myostatin propeptide is the natural inhibitor fragment of myostatin, discussed for muscle growth with cell and animal literature only.

Full profileSingle peptideMuscle growth and performance
Evidence unclearNot FDA-approved for listed uses
Dgrade

SHLP2

SHLP2 is a mitochondrial-derived peptide with early cell and rodent metabolic literature. It has no human data and no real-world use culture to speak of.

Full profileSingle peptideMitochondrial and longevity
Mostly preclinicalNot FDA-approved for listed uses
Cgrade

Cerebrolysin

Cerebrolysin is a porcine brain-derived peptide mixture used as a drug in some countries for stroke and dementia. It has many human trials, but the evidence base is contested and largely manufacturer-linked.

Full profileRelated compoundNeuro and cognition
Moderate human evidenceVaries by product and jurisdiction
Egrade

Gut Inflammation Blend

Gut-inflammation blends are vendor combinations, typically BPC-157 and KPV with or without TB-500, marketed for digestive claims. No blended product has controlled human evidence.

Full profileBlendImmune and inflammation
Evidence unclearNot FDA-approved for listed uses