Foundation

Storage and reconstitution basics

Why most peptides ship as freeze-dried powder, how reconstitution changes stability, and the math behind drawing an accurate amount.

Short answer

Most peptide products are stable as freeze-dried powder and fragile once mixed with liquid. Reconstitution turns a shelf-stable vial into a perishable one, and every amount drawn afterward depends on the concentration you created.

Why peptides ship lyophilized

Freeze-drying removes water, which is where most peptide degradation happens. Dry vials tolerate shipping and room-temperature storage far better than solutions do.

What changes after you add liquid

Once reconstituted, the clock starts. Refrigeration slows degradation, and pharmacy and community practice generally treats a multi-dose vial as about a 28-day supply. Heat, light, and repeated warming cycles all accelerate breakdown.

Why bacteriostatic water is the default

Bacteriostatic water contains a small amount of benzyl alcohol that inhibits bacterial growth across multiple withdrawals from the same vial. Plain sterile water is treated as single-use by convention.

The concentration you created is the amount you get

Adding 2 mL to a 10 mg vial makes a 5 mg/mL solution; every draw afterward is arithmetic on that number. The reconstitution calculator on this site converts vial amounts, water volumes, and U-100 syringe units.

Storage mistakes that quietly ruin vials

Freezing a reconstituted solution unless the specific product allows it, leaving vials in cars or on counters, and using a solution that has turned cloudy or shows particles. A visibly wrong solution is a discard, not a dose.

Sources

  1. 1.

    FDA. FDA to Compounders: Know Your Bulks and Excipients Suppliers 2026.

    Accessed 2026-06-09.

    FDA supplier-quality guidance for compounders; used for product-quality context, not as evidence of NAD+ efficacy or route instructions.

  2. 2.

    FDA. Compounding and the FDA: Questions and Answers 2026.

    Accessed 2026-06-08.

    FDA explains that compounded drugs are not FDA-approved and that FDA does not verify their safety, effectiveness, or quality before marketing.